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Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk)

Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk)
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk)

Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk)

Cat No.: RPC057Mu01 | Size: 10µg, 50µg, 200µg, 1mg, 5mg

Synonyms

CD265; TNFRSF11A; TNFRSF11-A; ODFR; OFE; TRANCER; Osteoclast differentiation factor receptor; Tumor Necrosis Factor Receptor Superfamily,Member 11a,NFKB Activator

SpeciesMus musculus (Mouse)
Expression HostE.coli
SequenceLI QQGKSKIPF QEPLVEGND SLSQCFTGTE STVDSECODF TEPPSRTDSM PVSPEKHLTK EIEGDSCLPW VVSSNTDGY TGSGNTPGED HEPFGSLKC GPLPQCAYSM GFPSEAAASM AEAGVRPQDR ADERGASGSG SSPSDQQPAS GNVTGNSNST FISSGQVNNF KGDIIVVYVS QT
AccessionO35305
Predicted Molecular Mass22.8kDa
Accurate Molecular Mass33kDa(Analysis of differences refer to the manual)
TagLeu359~Thr542 with N-terminal His Tag
Purity> 95%
Endotoxin<1.0EU per 1µg (determined by the LAL method)
StorageAvoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
ShippingThis product is provided as lyophilized powder which is shipped with ice packs.
Buffer FormulationPBS, pH7.4, containing 5% Trehalose.
ReconstitutionPlease refer to the printed manual for detailed information.
BackgroundRecombinant Receptor Activator of Nuclear Factor Kappa B (RANK, TNFRSF11A) is a bioactive protein that plays a key role in bone metabolism, immune regulation, and inflammatory responses. As a member of the TNF receptor superfamily, RANK interacts with its ligand (RANKL) to activate osteoclast differentiation, NF-κB signaling, and downstream pathways critical for bone resorption and immune function. This recombinant protein is widely used in research on osteoporosis, autoimmune diseases, and cancer metastasis. Suitable for in vitro assays, cell signaling studies, and drug discovery applications.

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